Abstract Background Volunteering participants in disease studies tend to be healthier than the general population partially due to specific enrollment criteria.Using modeling to accurately predict outcomes of cohort studies enrolling volunteers requires adjusting for the bias introduced in this way.Here we propose a new method to account for the ef
The livestock Body Spray sector is one of the fastest growing subsectors of the agricultural economy and, while it makes a major contribution to global food supply and economic development, it also consumes significant amounts of natural resources and alters the environment.In order to improve our understanding of the global environmental impact of
The RSK2 kinase is a downstream effector of the Ras/Raf/MEK/ERK pathway that is aberrantly active in a range of cancer types and has been recognized an anticancer target.The inhibition of RSK2 kinase activity would disrupt multiple pro-cancer processes; however, there are few RSK2 inhibitors.The Body Spray data have been obtained for a series of pt
Neuroinflammation is an important factor in the pathogenesis of neurodegenerative diseases.Microglia-derived lysosomal cathepsins have been increasingly recognized as important inflammatory mediators that Body Spray trigger signaling pathways that aggravate neuroinflammation.In vitro, a contribution to neuroinflammation processes has been shown for